Chemo-profiling of aqueous extract of Nauclea latifolia using GC-MS

Ojochenemi Ejeh Yakubu; Isaac John Umaru; Francis Onakpa Atanu; Kenneth Chinekwu Ugwuoke; Bilyaminu Habibu

doi:10.52679/tabcj.2023.0009

Authors

Ojochenemi Ejeh Yakubu Biochemistry Department, Federal University Wukari, Taraba State, Nigeria https://orcid.org/0000-0001-7168-6191
Isaac John Umaru Biochemistry Department, Federal University Wukari, Taraba State, Nigeria https://orcid.org/0000-0002-2800-0024
Francis Onakpa Atanu Department of Biochemistry, Prince Abubakar Audu University, Anyigba, Kogi State, Nigeria https://orcid.org/0000-0002-0817-0106
Kenneth Chinekwu Ugwuoke Biochemistry Department, Federal University Wukari, Taraba State, Nigeria https://orcid.org/0000-0003-3317-3023
Bilyaminu Habibu Biochemistry Department, Federal University Wukari, Taraba State, Nigeria https://orcid.org/0000-0002-2664-7764

DOI:

https://doi.org/10.52679/tabcj.2023.0009

Keywords:

Nauclea latifolia, ethnomedicine, medicinal plants, chemo-profiling, gas chromatography mass spectroscopy, aqueous extract

Abstract

This study is aimed at ascertaining the chemical profile of an aqueous Nauclea latifolia extract using gas chromatography mass spectroscopy (GC-MS). The plant extract underwent GC-MS analysis, and the mass spectra of the components were compared with that from the National Institute of Standards and Technology library (NIST). GC-MS analysis revealed 18 compounds from the aqueos extract of N. latifolia. Among them, 9- octadecenoic acid (Z)-methyl ester, oleic acid and benzamide-2-bromo-N-[2-(3- fluorophenyl)-5-benzoxazolyl] were found to be the most prevalent compounds with percentage areas of 16.93%, 14.01%, and 9.18%, respectively. Whereas, 5-methyl-2- phenylindolizine with a percentage area of 0.66% was the least abundant compound. Some of these phytocompounds present in the aqueous extract of N. latifolia possess several biological activities such as anti-inflammatory, antibacterial, and antimalarial properties. Hence, the aqueous extract of the leaf of N. latifolia can serve as a potential source of treatment in ethnomedicine.